There are most likely no direct flights on the Calama — La Serena route
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A non-stop flight is the most convenient and comfortable way to fly from Calama to La Serena, despite the fact that sometimes flights with transfers can cost significantly less.
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Answers to questions about the route that travelers are most interested in.
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There are most likely no direct flights on the Calama — La Serena route
Calama — La Serena
06/02/2026
Departure
Direct flight
LA395
starting at $74
Calama — La Serena
06/07/2026
Departure
Direct flight
LA395
starting at $42
Calama — La Serena
07/21/2026
Departure
Direct flight
H21741
starting at $64
Calama — La Serena
07/28/2026
Departure
Direct flight
LA395
starting at $43
starting at $42
starting at $28
Flights from Calama to La Serena are operated by several airlines — LATAM Chile and Sky Airline. This allows passengers to flexibly choose flights based on departure time, cost, and additional services. The minimum ticket price starts at $28, making this destination accessible to travelers with different budgets. We help compare all available options in real time, so you can book tickets at the best value for money. The service ensures transparent search and lets you book affordable flights in just a few clicks.
The cheapest one-way flight from Calama to La Serena departs on 07/21/2026, is operated by Sky Airline and costs $28
There is no information about the cheapest roundtrip flight from Calama to La Serena
Fastest flight from Calama to La Serena takes 1h 37m
There are direct flights on this route 2 days a week: Su and Tu
The distance between Calama and La Serena is 856km (531 miles). Calama and La Serena are in the same time zone
We couldn't find any special offers for flights from Calama to La Serena
The cheapest flight ticket from Calama to La Serena according to data for the last 48 hours costs $28
Often the best time to buy tickets from Calama to La Serena is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Calama to La Serena can be found flying in these months: July, June.
The fastest flights from Calama to La Serena start from 1 hour 37 minutes in the air.
The following airlines operate direct flights on the route Calama — La Serena: LATAM Chile, Sky Airline
The cost of a one-way flight from Calama to La Serena ranges from $28 (July 2026) to $42 (June 2026). On average, the ticket price is about $35–$42.