Cheap Flights from Cartagena to Panama City

Cheapest flights from Cartagena to Panama City

Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Cartagena to Panama City. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.

Cheapest one way flight

$164

Avianca

1 transfer

6h 45m

12/31/2025

The cheapest one-way flight from Cartagena to Panama City departs on 12/31/2025, is operated by Avianca and costs $164

Cheapest round trip flight

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There is no information about the cheapest roundtrip flight from Cartagena to Panama City

The fastest flight

4h 30m

Fastest flight from Cartagena to Panama City takes 4h 30m

Direct flights

No direct flights

There are no direct flights on this route.

Earliest flight

6:25 AM

Latest flight

3:04 PM

Direct flights count

33

Distance

467km

Timezone difference

0h

The distance between Cartagena and Panama City is 467km (290 miles). There are 33 direct flights from Cartagena to Panama City. Cartagena and Panama City are in the same time zone. Flights from Cartagena begin at 6:25 AM. The latest flight from Cartagena departs at 3:04 PM

Remember that on average the ideal time to book flights is 2 months before departure!

Airfare from Cartagena to Panama City by month

The cost of a one-way flight from Cartagena to Panama City ranges from $164 (December 2025) to $174 (April 2026). On average, the ticket price is about $168–$339.

December 2025

Lowest price

on average:

$164

April 2026

Highest price

on average:

$174

Avg Price

Airlines operating on route

Flights from Cartagena to Panama City are operated by several airlines — Copa Airlines and Avianca. This allows passengers to flexibly choose flights based on departure time, cost, and additional services. The minimum ticket price starts at $164, making this destination accessible to travelers with different budgets. We help compare all available options in real time, so you can book tickets at the best value for money. The service ensures transparent search and lets you book affordable flights in just a few clicks.

Copa Airlines

Starting at $194

Avianca

Starting at $164

Direct Flights from Cartagena to Panama City

A direct flight is the most convenient and comfortable way to fly from Cartagena to Panama City, despite the fact that sometimes flights with transfers can cost significantly less.

Cartagena — Panama City

CTG — PTY

12/31/2025

Departure

Direct flight

CM365

Starting at $241

Cartagena — Panama City

CTG — PTY

01/06/2026

Departure

Direct flight

CM453

Starting at $457

Cartagena — Panama City

CTG — PTY

01/10/2026

Departure

Direct flight

CM453

Starting at $409

Cartagena — Panama City

CTG — PTY

01/18/2026

Departure

Direct flight

CM203

Starting at $293

Cartagena — Panama City

CTG — PTY

01/20/2026

Departure

Direct flight

CM203

Starting at $195

Cartagena — Panama City

CTG — PTY

04/09/2026

Departure

Direct flight

CM160

Starting at $194

Schedule of direct flights from Cartagena to Panama City

A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Cartagena to Panama City:

Copa Airlines

Every day

Starting at $187

Cartagena airports overview

Rafael Nunez International Airport

•

CTG

•

Panama City airports overview

Marcos A. Gelabert International Airport

•

PAC

34km

Tocumen International Airport

•

PTY

17km

•

Frequently asked questions (FAQ)

Answers to questions about the route that travelers are most interested in.

How much is the cheapest flight ticket from Cartagena to Panama City?

The cheapest flight ticket from Cartagena to Panama City according to data for the last 48 hours costs $164

When is the best time to buy air tickets on the route Cartagena — Panama City?

Often the best time to buy tickets from Cartagena to Panama City is 2 months before departure.

When is the cheapest time of year to fly from Cartagena to Panama City?

Based on statistics over the past years, the lowest prices for flights from Cartagena to Panama City can be found flying in these months: December, January, April.

How long does it take to fly from Cartagena to Panama City?

The fastest flights from Cartagena to Panama City start from 4 hours 30 minutes in the air.

Which airline can fly direct from Cartagena to Panama City?

The following airlines operate direct flights on the route Cartagena — Panama City: Copa Airlines

Special offers and sales on air tickets from Cartagena to Panama City

We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.

We couldn't find any special offers for flights from Cartagena to Panama City

Alternative routes

Apartado ➜ Panama City•Barranquilla ➜ Panama City•Bucaramanga ➜ Panama City•Cucuta ➜ Panama City•Barrancabermeja ➜ Panama City•Maracaibo ➜ Panama City•Monteria ➜ Panama City•Riohacha ➜ Panama City•Santa Marta ➜ Panama City•Valledupar ➜ Panama City•Cartagena ➜ Apartado•Cartagena ➜ Barranquilla•Cartagena ➜ Cartago•Cartagena ➜ Cartagena•Cartagena ➜ David•Cartagena ➜ Medellin•Cartagena ➜ Monteria•Cartagena ➜ Pereira•Cartagena ➜ Quibdo

•••••••••••••••••••

Cheapest one way flight

$164

Avianca

1 transfer

6h 45m

12/31/2025

The cheapest one-way flight from Cartagena to Panama City departs on 12/31/2025, is operated by Avianca and costs $164

Cheapest round trip flight

—

There is no information about the cheapest roundtrip flight from Cartagena to Panama City

The fastest flight