starting at $283
starting at $100
Compare airlines, prices, and flight durations for your trip
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Chicago to Knoxville:
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Looking for cheap flights from Chicago to Knoxville? Look no further! Our air ticket search website offers the best deals and lowest fares for your travel needs. Whether you're planning a business trip or a weekend getaway, we've got you covered. With our user-friendly platform, you can easily compare prices from various airlines and choose the most affordable option that suits your budget. Our advanced search engine ensures you find the cheapest flights available, saving you both time and money. Experience the charm of Knoxville without breaking the bank. From its vibrant music scene to its historical landmarks, this city has something for everyone. So, why wait? Start your adventure today by booking your flight with us. Enjoy a stress-free journey from Chicago to Knoxville, knowing you got the best deal possible. Don't miss out on this opportunity to score cheap flights to Knoxville. Visit our website now and secure your tickets before they're gone!
The Chicago — Knoxville route is served by multiple airlines, including United Airlines and American Airlines. This is convenient for those who want the best balance of price, schedule, and travel conditions. Tickets start from $100, and depending on season and promotions, even better deals may appear. With our service, you can easily compare available options and book tickets that match your plans. The variety of carriers allows flexible choices and comfortable travel without overpaying.
starting at $283
starting at $100
Looking for direct flights from Chicago to Knoxville? Look no further! Fly hassle-free with direct flights from Chicago to Knoxville, conveniently connecting these two vibrant cities. Enjoy the convenience of a non-stop journey, saving you time and eliminating the need for transfers. However, if you can't find any direct flights, don't worry! There are alternative routes to reach Knoxville from Chicago. You can opt for connecting flights via major hubs like Atlanta, Charlotte, or Dallas. These routes offer seamless connections and numerous flight options to suit your travel preferences. At our air ticket search website, we provide you with a range of choices, including flights with or without transfers. Compare prices, flight durations, and schedules to find the best option for your travel needs. Don't let the absence of direct flights deter you, as we ensure convenient and affordable travel from Chicago to Knoxville. Start your search now, and embark on a memorable journey!
Chicago — Knoxville
01/30/2026
Departure
Direct flight
UA5588
starting at $283
Chicago — Knoxville
02/09/2026
Departure
Direct flight
AA5181
starting at $136
Chicago — Knoxville
12/10/2026
Departure
Direct flight
AA6223
starting at $227
Unable to find information about the schedule of direct flights from
The cheapest one-way flight from Chicago to Knoxville departs on 02/10/2026, is operated by American Airlines and costs $100
The cheapest roundtrip flight from Chicago to Knoxville departs on 02/01/2026, is operated by American Airlines and costs $228
Fastest flight from Chicago to Knoxville takes 1h 40m
There are direct flights on this route 3 days a week: Mo, Th, and Fr
The distance between Chicago and Knoxville is 744km (461 miles). The time difference between Chicago and Knoxville is 1h
We couldn't find any special offers for flights from Chicago to Knoxville
The cheapest flight ticket from Chicago to Knoxville according to data for the last 48 hours costs $100
Often the best time to buy tickets from Chicago to Knoxville is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Chicago to Knoxville can be found flying in these months: February, December, January.
The fastest flights from Chicago to Knoxville start from 1 hour 40 minutes in the air.
The following airlines operate direct flights on the route Chicago — Knoxville: United Airlines, American Airlines
In different months, ticket prices from Chicago to Knoxville vary: minimum — $100 (February 2026), maximum — $272 (January 2026). Typically, the flight costs $171–$414.