Helping travelers to find the best flight offers
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Des Moines to Chicago. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
A direct flight is the most convenient and comfortable way to fly from Des Moines to Chicago, despite the fact that sometimes flights with transfers can cost significantly less.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Des Moines to Chicago:
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We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Flights from Des Moines to Chicago are operated by several airlines — American Airlines, United Airlines, and Southwest Airlines. This allows passengers to flexibly choose flights based on departure time, cost, and additional services. The minimum ticket price starts at $95, making this destination accessible to travelers with different budgets. We help compare all available options in real time, so you can book tickets at the best value for money. The service ensures transparent search and lets you book affordable flights in just a few clicks.
Des Moines — Chicago
12/07/2025
Departure
Direct flight
AA4404
Starting at $213
Des Moines — Chicago
02/10/2026
Departure
Direct flight
AA4996
Starting at $200
Des Moines — Chicago
05/11/2026
Departure
Direct flight
UA1410
Starting at $214
Des Moines — Chicago
05/15/2026
Departure
Direct flight
UA3433
Starting at $183
Des Moines — Chicago
05/16/2026
Departure
Direct flight
UA1410
Starting at $195
Des Moines — Chicago
05/17/2026
Departure
Direct flight
WN2128
Starting at $164
Des Moines — Chicago
05/18/2026
Departure
Direct flight
UA312
Starting at $442
Unable to find information about the schedule of direct flights from
The cheapest one-way flight from Des Moines to Chicago departs on 02/10/2026, is operated by Southwest Airlines and costs $95
The cheapest roundtrip flight from Des Moines to Chicago departs on 12/13/2025, is operated by United Airlines and costs $224
Fastest flight from Des Moines to Chicago takes 1h 20m
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RFD
There are direct flights on this route 4 days a week: Su, Mo, Fr, and Sa
The distance between Des Moines and Chicago is 500km (310 miles). There are 78 direct flights from Des Moines to Chicago. Des Moines and Chicago are in the same time zone. Flights from Des Moines begin at 5:30 AM. The latest flight from Des Moines departs at 7:06 PM
The cheapest flight ticket from Des Moines to Chicago according to data for the last 48 hours costs $95
Often the best time to buy tickets from Des Moines to Chicago is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Des Moines to Chicago can be found flying in these months: May.
The fastest flights from Des Moines to Chicago start from 1 hour 20 minutes in the air.
The following airlines operate direct flights on the route Des Moines — Chicago: American Airlines, United Airlines, Southwest Airlines
We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Des Moines to Chicago
