Helping travelers to find the best flight offers
A direct flight is the most convenient and comfortable way to fly from Detroit to San Francisco, despite the fact that sometimes flights with transfers can cost significantly less.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Detroit to San Francisco:
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We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Looking for cheap flights from Detroit to San Francisco? Look no further! Our air ticket search website offers a wide selection of affordable flights to suit your travel needs. Whether you're planning a weekend getaway or a business trip, we have got you covered. With our user-friendly interface, finding the best deals has never been easier. Simply enter your travel dates, and we will provide you with a list of options from various airlines. You can easily compare prices, choose the most convenient departure and arrival times, and book your ticket within minutes. San Francisco is a vibrant city known for its stunning landmarks, diverse culture, and tech-savvy atmosphere. Don't miss out on exploring the Golden Gate Bridge, Alcatraz Island, and Fisherman's Wharf. Book your cheap flight from Detroit to San Francisco today and start your unforgettable journey.
Unable to find information about the schedule of direct flights from
Detroit — San Francisco
12/12/2025
Departure
Direct flight
UA578
Starting at $557
Detroit — San Francisco
12/13/2025
Departure
Direct flight
UA578
Starting at $548
Detroit — San Francisco
01/05/2026
Departure
Direct flight
UA551
Starting at $312
Starting at $312
Starting at $110
Starting at $138
Starting at $149
More than 4 airlines operate flights from Detroit to San Francisco, including United Airlines, Southwest Airlines, Spirit Airlines, and Frontier Airlines. This is a popular route, so passengers can choose tickets based on budget and preferences. Ticket prices start from $110, and our service lets you instantly compare all options. The variety of offers simplifies planning: you can choose budget fares or more comfortable options with baggage included or extra services. We help you find the best deals so your trip is cost-efficient.
The cheapest one-way flight from Detroit to San Francisco departs on 12/12/2025, is operated by Southwest Airlines and costs $110
The cheapest roundtrip flight from Detroit to San Francisco departs on 12/24/2025, is operated by Frontier Airlines and costs $228
Fastest flight from Detroit to San Francisco takes 7 hours
There are no direct flights on this route.
The distance between Detroit and San Francisco is 3358km (2082 miles). There are 36 direct flights from Detroit to San Francisco. The time difference between Detroit and San Francisco is 3h. Flights from Detroit begin at 8:25 AM. The latest flight from Detroit departs at 8:55 PM
We couldn't find any special offers for flights from Detroit to San Francisco
The cheapest flight ticket from Detroit to San Francisco according to data for the last 48 hours costs $110
Often the best time to buy tickets from Detroit to San Francisco is 2 months before departure.
The fastest flights from Detroit to San Francisco start from 7 hours in the air.
The following airlines operate direct flights on the route Detroit — San Francisco: United Airlines
We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Detroit to San Francisco