starting at $171
Compare airlines, prices, and flight durations for your trip
A non-stop flight is the most convenient and comfortable way to fly from Guatemala City to Santo Domingo, despite the fact that sometimes flights with transfers can cost significantly less.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Guatemala City to Santo Domingo:
•
•
•
•
•
•
Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Looking for cheap flights from Guatemala City, Guatemala to Santo Domingo, Dominican Republic? Look no further! Our air ticket search website offers the best deals to get you to your destination without breaking the bank. With our user-friendly interface, finding the most affordable options has never been easier. Discover a wide range of flight options from various airlines, allowing you to choose the one that suits your budget and preferences. Whether you're planning a relaxing getaway or an adventurous trip, saving money on your flights means more to spend on exploring the vibrant streets of Santo Domingo. So, why wait? Start your search now and secure the best deals on cheap flights from Guatemala City to Santo Domingo. Book your tickets with us today and enjoy a hassle-free travel experience while keeping your wallet happy. Don't miss out – start planning your dream trip now!
The route Guatemala City — Santo Domingo is served by a single airline — Asian Air. This means that when planning your trip, you won’t need to spend time choosing between dozens of carriers: all flights are operated by one provider, which simplifies the booking process. Despite the limited choice, passengers can still plan ahead, select optimal departure dates, and buy tickets at the lowest price — from $171. Using our service, you can quickly compare available Asian Air flights and book a seat in advance at a favorable rate.
starting at $171
Guatemala City — Santo Domingo
04/09/2026
Departure
Direct flight
DM4601
starting at $171
Unable to find information about the schedule of direct flights from
The cheapest one-way flight from Guatemala City to Santo Domingo departs on 04/09/2026, is operated by Asian Air and costs $171
The cheapest roundtrip flight from Guatemala City to Santo Domingo departs on 03/31/2026, is operated by Copa Airlines and costs $568
Fastest flight from Guatemala City to Santo Domingo takes 3h 34m
There are direct flights on this route 1 day a week: Th
The distance between Guatemala City and Santo Domingo is 2231km (1383 miles). The time difference between Guatemala City and Santo Domingo is 2h
We couldn't find any special offers for flights from Guatemala City to Santo Domingo
The cheapest flight ticket from Guatemala City to Santo Domingo according to data for the last 48 hours costs $171
Often the best time to buy tickets from Guatemala City to Santo Domingo is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Guatemala City to Santo Domingo can be found flying in these months: April.
The fastest flights from Guatemala City to Santo Domingo start from 3 hours 34 minutes in the air.
The following airlines operate direct flights on the route Guatemala City — Santo Domingo: Asian Air
We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Guatemala City to Santo Domingo