Cheapest one way flight
$155
Avianca
1 layover
4h 55m
02/03/2026
The cheapest one-way flight from Guayaquil to Panama City departs on 02/03/2026, is operated by Avianca and costs $155
Cheapest round trip flight
$304
Avianca
1 layover
10h 50m
02/03/2026
The cheapest roundtrip flight from Guayaquil to Panama City departs on 02/03/2026, is operated by Avianca and costs $304
The fastest flight
4h 55m
Fastest flight from Guayaquil to Panama City takes 4h 55m
Direct flights
Several times a week
There are direct flights on this route 4 days a week: Su, Tu, Th, and Sa
Earliest flight
4:32 AM
Latest flight
6:34 PM
Average flight duration
2h 11m
Direct flights count
40
Distance
1238km
Timezone difference
0h
The distance between Guayaquil and Panama City is 1238km (768 miles). The average flight duration is 2h 11m. There are 40 direct flights from Guayaquil to Panama City. Guayaquil and Panama City are in the same time zone. Flights from Guayaquil begin at 4:32 AM. The latest flight from Guayaquil departs at 6:34 PM
