Cheapest one way flight
$169
Avianca Ecuador
1 transfer
13h 55m
02/04/2026
The cheapest one-way flight from Guayaquil to Panama City departs on 02/04/2026, is operated by Avianca Ecuador and costs $169
Cheapest round trip flight
$349
Avianca
1 transfer
12h 5m
12/22/2025
The cheapest roundtrip flight from Guayaquil to Panama City departs on 12/22/2025, is operated by Avianca and costs $349
The fastest flight
2h 12m
Fastest flight from Guayaquil to Panama City takes 2h 12m
Direct flights
Once a week
There are direct flights on this route 1 day a week: Sa
Earliest flight
4:32 AM
Latest flight
6:34 PM
Average flight duration
2h 11m
Direct flights count
40
Distance
1238km
Timezone difference
0h
The distance between Guayaquil and Panama City is 1238km (768 miles). The average flight duration is 2h 11m. There are 40 direct flights from Guayaquil to Panama City. Guayaquil and Panama City are in the same time zone. Flights from Guayaquil begin at 4:32 AM. The latest flight from Guayaquil departs at 6:34 PM
