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Flying from Medellin to Cali is quick and simple — compare direct and connecting options to match your timing and comfort for this popular domestic route. We search more than 700 airlines, more than 50 agencies and more than 5 top booking systems to find the best prices, schedules and booking conditions so you can secure the right flight in minutes.
Direct flights from Medellín to Cali are the quickest and most convenient way to travel between these Colombian cities—perfect if you want to minimize hassle and maximize comfort. Although connecting options can sometimes be cheaper, nonstop service saves valuable time and makes the trip far more relaxing, so consider booking a direct flight for the smoothest journey.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Medellin to Cali:
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Unable to find information about the schedule of direct flights from
José María Córdova International Airport (MDE) is Medellín’s main international gateway, typically serving a mix of full‑service and low‑cost carriers and functioning as the region’s primary long‑haul hub. Located in Rionegro about 30–40 km east of the city center, transfers commonly take 45–90 minutes depending on traffic. Options include airport shuttles and buses to El Poblado and downtown, plus taxis or ride‑hailing that can roughly range from COP 80,000–150,000 (about USD 20–40) one way; car rental and parking are widely available. The airport usually offers modern terminals and duty‑free shopping, but its distance from central Medellín and variable traffic can add time and cost to trips.
Medellin — Cali
02/01/2026
Departure
Direct flight
VE6925
starting at $167
starting at $167
starting at $71
Flights from Medellin to Cali are operated by several airlines — C.A.I. Second and B&H Airlines. This allows passengers to flexibly choose flights based on departure time, cost, and additional services. The minimum ticket price starts at $71, making this destination accessible to travelers with different budgets. We help compare all available options in real time, so you can book tickets at the best value for money. The service ensures transparent search and lets you book affordable flights in just a few clicks.
The cheapest one-way flight from Medellin to Cali departs on 02/01/2026, is operated by B&H Airlines and costs $71
There is no information about the cheapest roundtrip flight from Medellin to Cali
Fastest flight from Medellin to Cali takes 1h 6m
There are direct flights on this route 1 day a week: Su
The distance between Medellin and Cali is 312km (193 miles). There are 28 direct flights from Medellin to Cali. Medellin and Cali are in the same time zone. Flights from Medellin begin at 4:40 AM. The latest flight from Medellin departs at 8:15 PM
Alfonso Bonilla Aragón (CLO) is Cali’s main international gateway and typically serves both full-service carriers and a mix of low-cost and regional operators — Avianca and LATAM plus Wingo, EasyFly and occasional international carriers. The airport sits outside the urban core (roughly 18 km from downtown), so transfers can be 20–40 minutes by car depending on traffic. Options include the city’s bus/MÍO connections (low single-ride fares), official taxis (roughly COP 30,000–60,000) and ride‑hailing or shuttle services (higher). Domestic routes can be competitively priced while international fares are usually mid-range; the terminal is convenient and modern but travel times can vary and late-night public links are limited.
We couldn't find any special offers for flights from Medellin to Cali
The cheapest flight ticket from Medellin to Cali according to data for the last 48 hours costs $71
Often the best time to buy tickets from Medellin to Cali is 2 months before departure.
The fastest flights from Medellin to Cali start from 1 hour 6 minutes in the air.
The following airlines operate direct flights on the route Medellin — Cali: C.A.I. Second
We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Medellin to Cali