Starting at $186
Starting at $158
Helping travelers to find the best flight offers
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Medellin to Panama City. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
A direct flight is the most convenient and comfortable way to fly from Medellin to Panama City, despite the fact that sometimes flights with transfers can cost significantly less.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Medellin to Panama City:
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We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
The route Medellin — Panama City is served by several airlines: Copa Airlines and Avianca. This gives passengers more freedom in choosing flights. You can consider not only the price but also schedules, baggage policies, and onboard service. Our service compares all offers so you can find tickets from $158 and choose the most convenient option. Thanks to airline competition, you may also find promotional fares or special offers, helping you save even more. Plan your trip in advance and choose the best flights without overpaying.
Starting at $186
Starting at $158
Medellin — Panama City
01/07/2026
Departure
Direct flight
CM398
Starting at $236
Medellin — Panama City
03/27/2026
Departure
Direct flight
CM209
Starting at $197
Medellin — Panama City
04/02/2026
Departure
Direct flight
CM209
Starting at $186
Medellin — Panama City
04/04/2026
Departure
Direct flight
CM506
Starting at $257
Unable to find information about the schedule of direct flights from
The cheapest one-way flight from Medellin to Panama City departs on 01/08/2026, is operated by Avianca and costs $158
The cheapest roundtrip flight from Medellin to Panama City departs on 12/09/2025, is operated by Avianca and costs $305
Fastest flight from Medellin to Panama City takes 1h 27m
There are direct flights on this route 2 days a week: Fr and Sa
The distance between Medellin and Panama City is 531km (329 miles). The average flight duration is 1h 28m. There are 72 direct flights from Medellin to Panama City. Medellin and Panama City are in the same time zone. Flights from Medellin begin at 5:00 AM. The latest flight from Medellin departs at 6:20 PM
We couldn't find any special offers for flights from Medellin to Panama City
The cheapest flight ticket from Medellin to Panama City according to data for the last 48 hours costs $158
Often the best time to buy tickets from Medellin to Panama City is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Medellin to Panama City can be found flying in these months: November.
The fastest flights from Medellin to Panama City start from 1 hour 27 minutes in the air.
The following airlines operate direct flights on the route Medellin — Panama City: Copa Airlines
We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Medellin to Panama City