Unable to find information about the schedule of direct flights from
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A non-stop flight is the most convenient and comfortable way to fly from Mexico City to Cali, despite the fact that sometimes flights with transfers can cost significantly less.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Mexico City to Cali:
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
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Unable to find information about the schedule of direct flights from
Mexico City — Cali
03/19/2026
Departure
Direct flight
AM754
starting at $313
Mexico City — Cali
03/27/2026
Departure
Direct flight
AM754
starting at $370
starting at $313
starting at $157
Flights from Mexico City to Cali are operated by several airlines — Aeromexico and Copa Airlines. This allows passengers to flexibly choose flights based on departure time, cost, and additional services. The minimum ticket price starts at $157, making this destination accessible to travelers with different budgets. We help compare all available options in real time, so you can book tickets at the best value for money. The service ensures transparent search and lets you book affordable flights in just a few clicks.
The cheapest one-way flight from Mexico City to Cali departs on 03/19/2026, is operated by Copa Airlines and costs $157
The cheapest roundtrip flight from Mexico City to Cali departs on 04/16/2026, is operated by Avianca and costs $282
Fastest flight from Mexico City to Cali takes 7h 11m
There are direct flights on this route 2 days a week: Th and Fr
The distance between Mexico City and Cali is 3035km (1882 miles). There are 1 direct flight from Mexico City to Cali. The time difference between Mexico City and Cali is 1h. Flights from Mexico City begin at 12:35 PM. The latest flight from Mexico City departs at 12:35 PM
We couldn't find any special offers for flights from Mexico City to Cali
The cheapest flight ticket from Mexico City to Cali according to data for the last 48 hours costs $157
Often the best time to buy tickets from Mexico City to Cali is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Mexico City to Cali can be found flying in these months: March.
The fastest flights from Mexico City to Cali start from 7 hours 11 minutes in the air.
The following airlines operate direct flights on the route Mexico City — Cali: Aeromexico
We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Mexico City to Cali