Cheap Flights from Mexico City to Santo Domingo

Cheapest flights from Mexico City to Santo Domingo

Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Mexico City to Santo Domingo. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.

Cheapest one way flight

$154

Asian Air

Direct flight

4h 15m

03/21/2026

The cheapest one-way flight from Mexico City to Santo Domingo departs on 03/21/2026, is operated by Asian Air and costs $154

Cheapest round trip flight

$389

Aeromexico

Direct flight

9h 7m

03/06/2026

The cheapest roundtrip flight from Mexico City to Santo Domingo departs on 03/06/2026, is operated by Aeromexico and costs $389

The fastest flight

4h 15m

Fastest flight from Mexico City to Santo Domingo takes 4h 15m

Direct flights

Several times a week

There are direct flights on this route 2 days a week: Fr and Sa

Earliest flight

11:44 PM

Latest flight

1:01 AM

Direct flights count

10

Distance

3062km

Timezone difference

2h

The distance between Mexico City and Santo Domingo is 3062km (1898 miles). There are 10 direct flights from Mexico City to Santo Domingo. The time difference between Mexico City and Santo Domingo is 2h. Flights from Mexico City begin at 11:44 PM. The latest flight from Mexico City departs at 1:01 AM

Remember that on average the ideal time to book flights is 2 months before departure!

Airfare from Mexico City to Santo Domingo by month

In different months, ticket prices from Mexico City to Santo Domingo vary: minimum — $154 (March 2026), maximum — $210 (December 2025). Typically, the flight costs $190–$416.

March 2026

Lowest price

on average:

$154

December 2025

Highest price

on average:

$210

Avg Price

Airlines operating on route

The route Mexico City — Santo Domingo is served by many carriers — 4 in total, including Asian Air, Aeromexico, Avianca, and Copa Airlines. This gives passengers wide opportunities: from finding the lowest fare (from $154) to selecting flights by schedule or service class. Our service aggregates data from multiple booking systems so you can compare offers in one place. This saves time and money: no need to check dozens of sites — just pick the right option and book online.

Starting at $154

Starting at $456

Starting at $205

Starting at $234

Direct Flights from Mexico City to Santo Domingo

A direct flight is the most convenient and comfortable way to fly from Mexico City to Santo Domingo, despite the fact that sometimes flights with transfers can cost significantly less.

Mexico City — Santo Domingo

MEX — SDQ

12/12/2025

Departure

Direct flight

DM4101

Starting at $245

Mexico City — Santo Domingo

MEX — SDQ

12/25/2025

Departure

Direct flight

DM4159

Starting at $330

Mexico City — Santo Domingo

MEX — SDQ

01/03/2026

Departure

Direct flight

AM654

Starting at $727

Mexico City — Santo Domingo

MEX — SDQ

01/30/2026

Departure

Direct flight

DM4101

Starting at $246

Mexico City — Santo Domingo

MEX — SDQ

03/20/2026

Departure

Direct flight

AM654

Starting at $456

Mexico City — Santo Domingo

MEX — SDQ

03/26/2026

Departure

Direct flight

AM654

Starting at $456

Schedule of direct flights from Mexico City to Santo Domingo

A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Mexico City to Santo Domingo:

Aeromexico

Every day

Starting at $446

Mexico City airports overview

Benito Juarez International Airport

•

MEX

6km

Felipe Angeles International Airport

•

NLU

4km

Toluca International Airport

•

TLC

59km

•

Santo Domingo airports overview

La Isabela International Airport

•

JBQ

9km

Las Americas International Airport

•

SDQ

34km

•

Frequently asked questions (FAQ)

Answers to questions about the route that travelers are most interested in.

How much is the cheapest flight ticket from Mexico City to Santo Domingo?

The cheapest flight ticket from Mexico City to Santo Domingo according to data for the last 48 hours costs $154

When is the best time to buy air tickets on the route Mexico City — Santo Domingo?

Often the best time to buy tickets from Mexico City to Santo Domingo is 2 months before departure.

When is the cheapest time of year to fly from Mexico City to Santo Domingo?

Based on statistics over the past years, the lowest prices for flights from Mexico City to Santo Domingo can be found flying in these months: March, January, December.

How long does it take to fly from Mexico City to Santo Domingo?

The fastest flights from Mexico City to Santo Domingo start from 4 hours 15 minutes in the air.

Which airline can fly direct from Mexico City to Santo Domingo?

The following airlines operate direct flights on the route Mexico City — Santo Domingo: Asian Air, Aeromexico

Special offers and sales on air tickets from Mexico City to Santo Domingo

We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.

We couldn't find any special offers for flights from Mexico City to Santo Domingo

Alternative routes

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Cheapest one way flight

$154

Asian Air

Direct flight

4h 15m

03/21/2026

The cheapest one-way flight from Mexico City to Santo Domingo departs on 03/21/2026, is operated by Asian Air and costs $154

Cheapest round trip flight

$389

Aeromexico

Direct flight

9h 7m

03/06/2026

The cheapest roundtrip flight from Mexico City to Santo Domingo departs on 03/06/2026, is operated by Aeromexico and costs $389

The fastest flight