Compare airlines, prices, and flight durations for your trip
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Panama City to Istanbul. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Panama City to Istanbul:
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Turkish Airlines
Every day
starting at $635
A non-stop flight is the most convenient and comfortable way to fly from Panama City to Istanbul, despite the fact that sometimes flights with transfers can cost significantly less.
Panama City — Istanbul
03/19/2026
Departure
Direct flight
TK801
starting at $1,751
Panama City — Istanbul
03/20/2026
Departure
Direct flight
TK800
starting at $1,773
Panama City — Istanbul
03/21/2026
Departure
Direct flight
TK801
starting at $1,720
Panama City — Istanbul
03/22/2026
Departure
Direct flight
TK800
starting at $1,774
Panama City — Istanbul
03/23/2026
Departure
Direct flight
TK801
starting at $1,937
Panama City — Istanbul
03/24/2026
Departure
Direct flight
TK900
starting at $1,805
Panama City — Istanbul
03/26/2026
Departure
Direct flight
TK904
starting at $1,375
Panama City — Istanbul
03/26/2026
Departure
Direct flight
TK801
starting at $1,801
Panama City — Istanbul
03/27/2026
Departure
Direct flight
TK800
starting at $1,845
Panama City — Istanbul
04/01/2026
Departure
Direct flight
TK900
starting at $1,752
starting at $687
starting at $607
starting at $596
starting at $613
More than 4 airlines operate flights from Panama City to Istanbul, including Turkish Airlines, Copa Airlines, Lufthansa, and United Airlines. This is a popular route, so passengers can choose tickets based on budget and preferences. Ticket prices start from $596, and our service lets you instantly compare all options. The variety of offers simplifies planning: you can choose budget fares or more comfortable options with baggage included or extra services. We help you find the best deals so your trip is cost-efficient.
The cheapest one-way flight from Panama City to Istanbul departs on 05/01/2026, is operated by Lufthansa and costs $596
The cheapest roundtrip flight from Panama City to Istanbul departs on 06/15/2026, is operated by Air Europa and costs $956
Fastest flight from Panama City to Istanbul takes 19h 15m
There are direct flights on this route 7 days a week: Su, Mo, Tu, We, Th, Fr, and Sa
The distance between Panama City and Istanbul is 10850km (6727 miles). The average flight duration is 12h 45m. There are 12 direct flights from Panama City to Istanbul. The time difference between Panama City and Istanbul is 8h. Flights from Panama City begin at 6:45 PM. The latest flight from Panama City departs at 9:45 PM
We couldn't find any special offers for flights from Panama City to Istanbul
The cheapest flight ticket from Panama City to Istanbul according to data for the last 48 hours costs $596
Often the best time to buy tickets from Panama City to Istanbul is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Panama City to Istanbul can be found flying in these months: November, April, May.
The fastest flights from Panama City to Istanbul start from 19 hours 15 minutes in the air.
The following airlines operate direct flights on the route Panama City — Istanbul: Turkish Airlines, Copa Airlines
The cost of a one-way flight from Panama City to Istanbul ranges from $607 (November 2026) to $647 (June 2026). On average, the ticket price is about $632–$1,265.