Cheap Flights from Panama City to Manaus

Cheapest flights from Panama City to Manaus

Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Panama City to Manaus. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.

Cheapest one way flight

$441

Avianca

2 transfers

1d 20h 45m

12/18/2025

The cheapest one-way flight from Panama City to Manaus departs on 12/18/2025, is operated by Avianca and costs $441

Cheapest round trip flight

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There is no information about the cheapest roundtrip flight from Panama City to Manaus

The fastest flight

1d 20h 45m

Fastest flight from Panama City to Manaus takes 1d 20h 45m

Direct flights

No direct flights

There are no direct flights on this route.

Earliest flight

9:27 PM

Latest flight

9:27 PM

Direct flights count

16

Distance

2538km

Timezone difference

1h

The distance between Panama City and Manaus is 2538km (1574 miles). There are 16 direct flights from Panama City to Manaus. The time difference between Panama City and Manaus is 1h. Flights from Panama City begin at 9:27 PM. The latest flight from Panama City departs at 9:27 PM

Remember that on average the ideal time to book flights is 2 months before departure!

Airfare from Panama City to Manaus by month

We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Panama City to Manaus

December 2025

Lowest price

on average:

$441

Avg Price

Airlines operating on route

The Panama City — Manaus route is served by multiple airlines, including Copa Airlines and Avianca. This is convenient for those who want the best balance of price, schedule, and travel conditions. Tickets start from $441, and depending on season and promotions, even better deals may appear. With our service, you can easily compare available options and book tickets that match your plans. The variety of carriers allows flexible choices and comfortable travel without overpaying.

Copa Airlines

Starting at $796

Avianca

Starting at $441

Direct Flights from Panama City to Manaus

A direct flight is the most convenient and comfortable way to fly from Panama City to Manaus, despite the fact that sometimes flights with transfers can cost significantly less.

Panama City — Manaus

PTY — MAO

12/19/2025

Departure

Direct flight

CM141

Starting at $796

Schedule of direct flights from Panama City to Manaus

A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Panama City to Manaus:

Unable to find information about the schedule of direct flights from

Panama City airports overview

Marcos A. Gelabert International Airport

•

PAC

34km

Tocumen International Airport

•

PTY

17km

•

Manaus airports overview

Eduardo Gomes International Airport

•

MAO

•

Frequently asked questions (FAQ)

Answers to questions about the route that travelers are most interested in.

How much is the cheapest flight ticket from Panama City to Manaus?

The cheapest flight ticket from Panama City to Manaus according to data for the last 48 hours costs $441

When is the best time to buy air tickets on the route Panama City — Manaus?

Often the best time to buy tickets from Panama City to Manaus is 2 months before departure.

When is the cheapest time of year to fly from Panama City to Manaus?

Based on statistics over the past years, the lowest prices for flights from Panama City to Manaus can be found flying in these months: December.

How long does it take to fly from Panama City to Manaus?

The fastest flights from Panama City to Manaus start from 20 hours 45 minutes in the air.

Which airline can fly direct from Panama City to Manaus?

The following airlines operate direct flights on the route Panama City — Manaus: Copa Airlines

Special offers and sales on air tickets from Panama City to Manaus

We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.

We couldn't find any special offers for flights from Panama City to Manaus

Alternative routes

Apartado ➜ Manaus•Barranquilla ➜ Manaus•Cartago ➜ Manaus•Cartagena ➜ Manaus•David ➜ Manaus•Medellin ➜ Manaus•Monteria ➜ Manaus•Pereira ➜ Manaus•Quibdo ➜ Manaus•Panama City ➜ Altamira•Panama City ➜ Belem•Panama City ➜ Ji-Parana•Panama City ➜ Maraba•Panama City ➜ Macapa•Panama City ➜ Paramaribo•Panama City ➜ Parintins•Panama City ➜ Porto Velho•Panama City ➜ Rio Branco•Panama City ➜ Santarem

•••••••••••••••••••

Cheapest one way flight

$441

Avianca

2 transfers

1d 20h 45m

12/18/2025

The cheapest one-way flight from Panama City to Manaus departs on 12/18/2025, is operated by Avianca and costs $441

Cheapest round trip flight

—

There is no information about the cheapest roundtrip flight from Panama City to Manaus

The fastest flight