Unable to find information about the schedule of direct flights from
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Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Panama City to Medellin. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
A direct flight is the most convenient and comfortable way to fly from Panama City to Medellin, despite the fact that sometimes flights with transfers can cost significantly less.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Panama City to Medellin:
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We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Unable to find information about the schedule of direct flights from
The cheapest one-way flight from Panama City to Medellin departs on 09/10/2026, is operated by Avianca and costs $157
The cheapest roundtrip flight from Panama City to Medellin departs on 02/20/2026, is operated by Copa Airlines and costs $249
Fastest flight from Panama City to Medellin takes 1h 23m
There are direct flights on this route 2 days a week: Tu and We
The distance between Panama City and Medellin is 531km (329 miles). There are 67 direct flights from Panama City to Medellin. Panama City and Medellin are in the same time zone. Flights from Panama City begin at 6:54 AM. The latest flight from Panama City departs at 9:23 PM
Panama City — Medellin
12/10/2025
Departure
Direct flight
CM208
Starting at $323
Panama City — Medellin
12/11/2025
Departure
Direct flight
CM156
Starting at $265
Panama City — Medellin
12/23/2025
Departure
Direct flight
CM397
Starting at $162
Panama City — Medellin
01/25/2026
Departure
Direct flight
CM756
Starting at $251
Panama City — Medellin
02/12/2026
Departure
Direct flight
P5502
Starting at $234
Panama City — Medellin
04/02/2026
Departure
Direct flight
CM756
Starting at $242
Panama City — Medellin
09/09/2026
Departure
Direct flight
CM397
Starting at $199
Panama City — Medellin
11/06/2026
Departure
Direct flight
CM155
Starting at $261
The Panama City — Medellin route is served by multiple airlines, including Copa Airlines, Aerorepublica, and Avianca. This is convenient for those who want the best balance of price, schedule, and travel conditions. Tickets start from $157, and depending on season and promotions, even better deals may appear. With our service, you can easily compare available options and book tickets that match your plans. The variety of carriers allows flexible choices and comfortable travel without overpaying.
We couldn't find any special offers for flights from Panama City to Medellin
The cheapest flight ticket from Panama City to Medellin according to data for the last 48 hours costs $157
Often the best time to buy tickets from Panama City to Medellin is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Panama City to Medellin can be found flying in these months: December, February, January.
The fastest flights from Panama City to Medellin start from 1 hour 23 minutes in the air.
The following airlines operate direct flights on the route Panama City — Medellin: Copa Airlines, Aerorepublica
In different months, ticket prices from Panama City to Medellin vary: minimum — $164 (December 2025), maximum — $166 (January 2026). Typically, the flight costs $165–$331.