Compare airlines, prices, and flight durations for your trip
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Panama City to Sao Paulo. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
A non-stop flight is the most convenient and comfortable way to fly from Panama City to Sao Paulo, despite the fact that sometimes flights with transfers can cost significantly less.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Panama City to Sao Paulo:
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
The cheapest one-way flight from Panama City to Sao Paulo departs on 03/11/2026, is operated by Avianca and costs $245
The cheapest roundtrip flight from Panama City to Sao Paulo departs on 03/08/2026, is operated by Copa Airlines and costs $405
Fastest flight from Panama City to Sao Paulo takes 10h 20m
There are direct flights on this route 7 days a week: Su, Mo, Tu, We, Th, Fr, and Sa
The distance between Panama City and Sao Paulo is 5089km (3155 miles). The average flight duration is 13h 38m. There are 10 direct flights from Panama City to Sao Paulo. The time difference between Panama City and Sao Paulo is 2h. Flights from Panama City begin at 11:45 AM. The latest flight from Panama City departs at 9:31 PM
The route Panama City — Sao Paulo is served by several airlines: Copa Airlines, Azul Brazilian Airlines, and Avianca. This gives passengers more freedom in choosing flights. You can consider not only the price but also schedules, baggage policies, and onboard service. Our service compares all offers so you can find tickets from $245 and choose the most convenient option. Thanks to airline competition, you may also find promotional fares or special offers, helping you save even more. Plan your trip in advance and choose the best flights without overpaying.
Panama City — Sao Paulo
02/02/2026
Departure
Direct flight
CM725
starting at $983
Panama City — Sao Paulo
02/14/2026
Departure
Direct flight
CM701
starting at $779
Panama City — Sao Paulo
02/15/2026
Departure
Direct flight
CM743
starting at $841
Panama City — Sao Paulo
02/16/2026
Departure
Direct flight
CM743
starting at $942
Panama City — Sao Paulo
02/18/2026
Departure
Direct flight
CM701
starting at $852
Panama City — Sao Paulo
02/20/2026
Departure
Direct flight
AD7565
starting at $925
Panama City — Sao Paulo
02/22/2026
Departure
Direct flight
CM759
starting at $968
Panama City — Sao Paulo
03/08/2026
Departure
Direct flight
CM701
starting at $821
Panama City — Sao Paulo
03/15/2026
Departure
Direct flight
CM725
starting at $607
Panama City — Sao Paulo
05/04/2026
Departure
Direct flight
CM759
starting at $896
Copa Airlines
Tu
starting at $456
The cheapest flight ticket from Panama City to Sao Paulo according to data for the last 48 hours costs $245
Often the best time to buy tickets from Panama City to Sao Paulo is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Panama City to Sao Paulo can be found flying in these months: May, March, December.
The fastest flights from Panama City to Sao Paulo start from 10 hours 20 minutes in the air.
The following airlines operate direct flights on the route Panama City — Sao Paulo: Copa Airlines, Azul Brazilian Airlines
The minimum one-way ticket price from Panama City to Sao Paulo is $283 (May 2026), while the maximum is $350 (February 2026). On average, a ticket costs $307–$310.