Ryanair
Th
starting at $60
Compare airlines, prices, and flight durations for your trip
A non-stop flight is the most convenient and comfortable way to fly from Pisa to Brussels, despite the fact that sometimes flights with transfers can cost significantly less.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Pisa to Brussels:
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Looking for cheap flights from Pisa, Italy to Brussels, Belgium? Look no further! Our air ticket search website offers unbeatable deals on this popular route. Whether you're planning a business trip or a well-deserved getaway, we've got you covered. Hop on a low-cost flight from Pisa and explore the historic city of Brussels without breaking the bank. Enjoy its picturesque streets, mouthwatering cuisine, and world-class attractions like the Grand Place and the Atomium. With convenient departure times and multiple airlines to choose from, finding the perfect flight has never been easier. Don't miss out on our exclusive offers and discounts! Just enter your travel dates, compare the prices, and book your affordable ticket in a matter of minutes. Start your journey from Pisa to Brussels today and experience the best of both worlds while saving money. Bon voyage!
Ryanair
Th
starting at $60
Pisa — Brussels
04/07/2026
Departure
Direct flight
FR5236
starting at $81
Pisa — Brussels
04/08/2026
Departure
Direct flight
MW3746
starting at $56
Pisa — Brussels
05/01/2026
Departure
Direct flight
FR3746
starting at $150
Pisa — Brussels
03/23/2026
Departure
Direct flight
MW3747
starting at $120
Pisa — Brussels
03/24/2026
Departure
Direct flight
MW3746
starting at $52
Pisa — Brussels
04/04/2026
Departure
Direct flight
FR5236
starting at $90
Pisa — Brussels
04/16/2026
Departure
Direct flight
FR3746
starting at $75
The route Pisa — Brussels is served by several airlines: Ryanair, Mokulele Airlines, and Wizz Air. This gives passengers more freedom in choosing flights. You can consider not only the price but also schedules, baggage policies, and onboard service. Our service compares all offers so you can find tickets from $25 and choose the most convenient option. Thanks to airline competition, you may also find promotional fares or special offers, helping you save even more. Plan your trip in advance and choose the best flights without overpaying.
The cheapest one-way flight from Pisa to Brussels departs on 04/08/2026, is operated by Mokulele Airlines and costs $25
The cheapest roundtrip flight from Pisa to Brussels departs on 03/19/2026, is operated by Mokulele Airlines and costs $187
Fastest flight from Pisa to Brussels takes 1h 40m
There are direct flights on this route 6 days a week: Mo, Tu, We, Th, Fr, and Sa
The distance between Pisa and Brussels is 916km (568 miles). There are 3 direct flights from Pisa to Brussels. Pisa and Brussels are in the same time zone. Flights from Pisa begin at 11:30 AM. The latest flight from Pisa departs at 4:30 PM
We couldn't find any special offers for flights from Pisa to Brussels
The cheapest flight ticket from Pisa to Brussels according to data for the last 48 hours costs $25
Often the best time to buy tickets from Pisa to Brussels is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Pisa to Brussels can be found flying in these months: April, March, January.
The fastest flights from Pisa to Brussels start from 1 hour 40 minutes in the air.
The following airlines operate direct flights on the route Pisa — Brussels: Ryanair, Mokulele Airlines
The minimum one-way ticket price from Pisa to Brussels is $25 (April 2026), while the maximum is $93 (May 2026). On average, a ticket costs $65–$92.
