starting at $249
starting at $262
starting at $348
starting at $358
Compare airlines, prices, and flight durations for your trip
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Santa Cruz to Sao Paulo. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
A non-stop flight is the most convenient and comfortable way to fly from Santa Cruz to Sao Paulo, despite the fact that sometimes flights with transfers can cost significantly less.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Santa Cruz to Sao Paulo:
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
The Santa Cruz — Sao Paulo route is served by a wide range of airlines: 4 in total, including Boliviana de Aviación, Gol Transportes Aéreos, Air Ocean, and Avianca. Competition among carriers gives passengers the opportunity to find tickets at attractive fares — with prices starting from $249. Our service helps compare all available offers within seconds and choose the most convenient option. You can filter flights by price, departure time, or baggage rules to make your trip as comfortable as possible. With so many airlines, there’s always a chance to catch special promotions and save.
starting at $249
starting at $262
starting at $348
starting at $358
Santa Cruz — Sao Paulo
04/19/2026
Departure
Direct flight
OB736
starting at $249
Santa Cruz — Sao Paulo
08/19/2026
Departure
Direct flight
OB736
starting at $251
Santa Cruz — Sao Paulo
10/28/2026
Departure
Direct flight
OB736
starting at $252
Santa Cruz — Sao Paulo
08/24/2026
Departure
Direct flight
OB736
starting at $257
Santa Cruz — Sao Paulo
08/26/2026
Departure
Direct flight
OB736
starting at $257
Santa Cruz — Sao Paulo
08/31/2026
Departure
Direct flight
OB736
starting at $257
Santa Cruz — Sao Paulo
03/04/2026
Departure
Direct flight
G37717
starting at $262
Santa Cruz — Sao Paulo
02/05/2026
Departure
Direct flight
G37717
starting at $262
Santa Cruz — Sao Paulo
03/20/2026
Departure
Direct flight
OB734
starting at $269
Santa Cruz — Sao Paulo
03/05/2026
Departure
Direct flight
OB736
starting at $294
Boliviana de Aviación
Su, Mo, Tu, Th, and Fr
starting at $249
Gol Transportes Aéreos
Su, Mo, Tu, Th, and Fr
starting at $262
We couldn't find any special offers for flights from Santa Cruz to Sao Paulo
The cheapest one-way flight from Santa Cruz to Sao Paulo departs on 04/19/2026, is operated by Boliviana de Aviación and costs $249
The cheapest roundtrip flight from Santa Cruz to Sao Paulo departs on 08/24/2026, is operated by Gol Transportes Aéreos and costs $311
Fastest flight from Santa Cruz to Sao Paulo takes 2h 40m
There are direct flights on this route 5 days a week: Su, Mo, We, Th, and Fr
The distance between Santa Cruz and Sao Paulo is 1836km (1138 miles). The average flight duration is 2h 45m. There are 15 direct flights from Santa Cruz to Sao Paulo. The time difference between Santa Cruz and Sao Paulo is 1h. Flights from Santa Cruz begin at 9:05 AM. The latest flight from Santa Cruz departs at 1:35 PM
The cheapest flight ticket from Santa Cruz to Sao Paulo according to data for the last 48 hours costs $249
Often the best time to buy tickets from Santa Cruz to Sao Paulo is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Santa Cruz to Sao Paulo can be found flying in these months: April, March, February.
The fastest flights from Santa Cruz to Sao Paulo start from 2 hours 40 minutes in the air.
The following airlines operate direct flights on the route Santa Cruz — Sao Paulo: Boliviana de Aviación, Gol Transportes Aéreos
The minimum one-way ticket price from Santa Cruz to Sao Paulo is $249 (April 2026), while the maximum is $262 (February 2026). On average, a ticket costs $258–$524.