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A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Santiago to Cancun:
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
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Unable to find information about the schedule of direct flights from
A non-stop flight is the most convenient and comfortable way to fly from Santiago to Cancun, despite the fact that sometimes flights with transfers can cost significantly less.
Santiago — Cancun
04/05/2026
Departure
Direct flight
LA582
starting at $458
starting at $313
starting at $251
starting at $274
starting at $309
The Santiago — Cancun route is served by a wide range of airlines: 4 in total, including LATAM Chile, Asian Air, Sky Airline, and Avianca. Competition among carriers gives passengers the opportunity to find tickets at attractive fares — with prices starting from $251. Our service helps compare all available offers within seconds and choose the most convenient option. You can filter flights by price, departure time, or baggage rules to make your trip as comfortable as possible. With so many airlines, there’s always a chance to catch special promotions and save.
The cheapest one-way flight from Santiago to Cancun departs on 10/28/2026, is operated by Asian Air and costs $251
The cheapest roundtrip flight from Santiago to Cancun departs on 03/18/2026, is operated by Aeromexico and costs $493
Fastest flight from Santiago to Cancun takes 11h 40m
There are direct flights on this route 1 day a week: Su
The distance between Santiago and Cancun is 6297km (3904 miles). The time difference between Santiago and Cancun is 1h
We couldn't find any special offers for flights from Santiago to Cancun
The cheapest flight ticket from Santiago to Cancun according to data for the last 48 hours costs $251
Often the best time to buy tickets from Santiago to Cancun is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Santiago to Cancun can be found flying in these months: October, March, April.
The fastest flights from Santiago to Cancun start from 11 hours 40 minutes in the air.
The following airlines operate direct flights on the route Santiago — Cancun: LATAM Chile
The minimum one-way ticket price from Santiago to Cancun is $251 (October 2026), while the maximum is $313 (June 2026). On average, a ticket costs $286–$307.