Helping travelers to find the best flight offers
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Santiago to Medellin:
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We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Looking for cheap flights from Santiago, Chile to Medellin, Colombia? Look no further! Our air ticket search website offers the best deals for your travel needs. Explore the vibrant city of Medellin, known for its warm hospitality and rich cultural heritage. Discover the picturesque landscapes, indulge in delicious cuisine, and immerse yourself in the local traditions. With our user-friendly interface, finding affordable flights has never been easier. Whether you're planning a business trip or a relaxing vacation, our website guarantees the cheapest fares available. Don't miss out on this opportunity to experience the charm of Medellin without breaking the bank. Book your flight today and start creating unforgettable memories in this enchanting Colombian destination!
More than 4 airlines operate flights from Santiago to Medellin, including B&H Airlines, Jet Ops, Copa Airlines, and LATAM Chile. This is a popular route, so passengers can choose tickets based on budget and preferences. Ticket prices start from $135, and our service lets you instantly compare all options. The variety of offers simplifies planning: you can choose budget fares or more comfortable options with baggage included or extra services. We help you find the best deals so your trip is cost-efficient.
Starting at $135
Starting at $592
Starting at $314
Starting at $328
Looking for direct flights from Santiago, Chile to Medellin, Colombia? Good news! You can hop on a direct flight and reach your destination without any layovers. Several airlines, such as Latam Airlines and Avianca, offer non-stop flights on this route, ensuring a convenient and time-saving journey. If, however, there are no available direct flights, don't worry! There are alternative routes with transfers that you can consider. Opt for a connecting flight via Bogota, Colombia, or Lima, Peru. Airlines like Copa Airlines and Viva Air offer seamless connections, allowing you to explore vibrant cities along the way. On our air ticket search website, you can effortlessly find the best fares and schedules for both direct and indirect flights. Explore various options and book your preferred flight now. Your adventure awaits in Medellin!
Santiago — Medellin
12/22/2025
Departure
Direct flight
JA5839
Starting at $497
Santiago — Medellin
01/19/2026
Departure
Direct flight
JA5839
Starting at $262
Santiago — Medellin
02/28/2026
Departure
Direct flight
JA5839
Starting at $135
Santiago — Medellin
11/30/2026
Departure
Direct flight
J65839
Starting at $592
Unable to find information about the schedule of direct flights from
When it comes to airports in Santiago, Chile, travelers are spoilt for choice. The main airport, Arturo Merino Benítez International Airport (SCL), is a bustling hub situated approximately 17 kilometers from the city center. Boasting a wide range of airlines, including renowned carriers like LATAM Airlines, this airport offers convenience and flexibility for travelers seeking affordable air tickets. Moreover, SCL is well-connected with the city by various transportation options, making it accessible for all travelers. For those looking for a more local experience, Comodoro Arturo Merino Benítez Air Base (PUD) is another option worth considering. This airport is located about 40 kilometers from Santiago and offers a quieter atmosphere. While it may be further from the city, budget-conscious travelers can take advantage of lower-priced airfares from select airlines. However, it's important to note that transportation options to PUD are more limited, and the extra distance may add to travel time and costs. Ultimately, the choice between the two airports depends on individual preferences. While SCL offers the convenience of being closer to the city and a wider range of airlines, PUD provides potential savings for those willing to venture a bit further. No matter which airport you choose, ensure to use our air tickets search website to secure the best deals and make your travel experience hassle-free!
The cheapest one-way flight from Santiago to Medellin departs on 02/28/2026, is operated by B&H Airlines and costs $135
The cheapest roundtrip flight from Santiago to Medellin departs on 01/17/2026, is operated by B&H Airlines and costs $507
Fastest flight from Santiago to Medellin takes 6h 15m
There are direct flights on this route 2 days a week: Mo and Sa
The distance between Santiago and Medellin is 4440km (2753 miles). There are 5 direct flights from Santiago to Medellin. The time difference between Santiago and Medellin is 1h. Flights from Santiago begin at 1:59 AM. The latest flight from Santiago departs at 1:59 AM
We couldn't find any special offers for flights from Santiago to Medellin
The cheapest flight ticket from Santiago to Medellin according to data for the last 48 hours costs $135
Often the best time to buy tickets from Santiago to Medellin is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Santiago to Medellin can be found flying in these months: February.
The fastest flights from Santiago to Medellin start from 6 hours 15 minutes in the air.
The following airlines operate direct flights on the route Santiago — Medellin: B&H Airlines, Jet Ops
We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Santiago to Medellin