Cheap Flights from Santiago to Panama City Starting at $644

You can fly from Santiago to Panama City with American Airlines. It is the only carrier on this route, which makes the choice straightforward. Despite the lack of competition, ticket prices remain affordable: fares start from $644. Our service helps you track price changes, compare by dates, and select the most suitable flight. If you value stability and predictability, flying with American Airlines is a convenient solution. We make it easy to find good deals and ensure a comfortable booking process.

A direct flight is the most convenient and comfortable way to fly from Santiago to Panama City, despite the fact that sometimes flights with transfers can cost significantly less.

We carefully collect statistics on the search and pricing of airlines and, based on these data, we make an assumption about future prices. Thus, you can better understand which season is the cheapest to fly from Santiago to Panama City