starting at $120
starting at $214
Compare airlines, prices, and flight durations for your trip
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Santo Domingo to Guatemala City. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
A non-stop flight is the most convenient and comfortable way to fly from Santo Domingo to Guatemala City, despite the fact that sometimes flights with transfers can cost significantly less.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Santo Domingo to Guatemala City:
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
The route Santo Domingo — Guatemala City is served by several airlines: Asian Air and Spirit Airlines. This gives passengers more freedom in choosing flights. You can consider not only the price but also schedules, baggage policies, and onboard service. Our service compares all offers so you can find tickets from $120 and choose the most convenient option. Thanks to airline competition, you may also find promotional fares or special offers, helping you save even more. Plan your trip in advance and choose the best flights without overpaying.
starting at $120
starting at $214
Santo Domingo — Guatemala City
02/16/2026
Departure
Direct flight
DM4660
starting at $204
Santo Domingo — Guatemala City
03/02/2026
Departure
Direct flight
DM4660
starting at $120
Santo Domingo — Guatemala City
04/04/2026
Departure
Direct flight
DM4602
starting at $556
Unable to find information about the schedule of direct flights from
The cheapest one-way flight from Santo Domingo to Guatemala City departs on 03/02/2026, is operated by Asian Air and costs $120
The cheapest roundtrip flight from Santo Domingo to Guatemala City departs on 07/06/2026, is operated by Asian Air and costs $324
Fastest flight from Santo Domingo to Guatemala City takes 3h 36m
There are direct flights on this route 2 days a week: Mo and Sa
The distance between Santo Domingo and Guatemala City is 2231km (1383 miles). There are 10 direct flights from Santo Domingo to Guatemala City. The time difference between Santo Domingo and Guatemala City is 2h. Flights from Santo Domingo begin at 6:00 AM. The latest flight from Santo Domingo departs at 6:20 PM
We couldn't find any special offers for flights from Santo Domingo to Guatemala City
The cheapest flight ticket from Santo Domingo to Guatemala City according to data for the last 48 hours costs $120
Often the best time to buy tickets from Santo Domingo to Guatemala City is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Santo Domingo to Guatemala City can be found flying in these months: March, February, April.
The fastest flights from Santo Domingo to Guatemala City start from 3 hours 36 minutes in the air.
The following airlines operate direct flights on the route Santo Domingo — Guatemala City: Asian Air
The minimum one-way ticket price from Santo Domingo to Guatemala City is $120 (March 2026), while the maximum is $214 (April 2026). On average, a ticket costs $167–$381.