Compare airlines, prices, and flight durations for your trip
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Sao Paulo to Santiago:
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Looking for cheap flights from Sao Paulo to Santiago? Your search ends here! Get ready to explore the vibrant city of Santiago without breaking the bank. Our air ticket search website offers you the most affordable deals and easy booking options. Discover the breathtaking beauty of the Andes, immerse yourself in the rich cultural heritage, and indulge in delicious Chilean cuisine, all at a budget-friendly price. With multiple airlines to choose from, finding your ideal flight has never been easier. So, why wait? Plan your trip now and embark on an unforgettable journey from Sao Paulo to Santiago. Don't miss out on these incredible savings – book your tickets today!
The Sao Paulo — Santiago route is served by a wide range of airlines: 7 in total, including B&H Airlines, Sky Airline, LATAM Chile, LATAM Brasil, Aerolineas Argentinas, Azul Brazilian Airlines, and Avianca. Competition among carriers gives passengers the opportunity to find tickets at attractive fares — with prices starting from $116. Our service helps compare all available offers within seconds and choose the most convenient option. You can filter flights by price, departure time, or baggage rules to make your trip as comfortable as possible. With so many airlines, there’s always a chance to catch special promotions and save.
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starting at $130
starting at $133
starting at $221
starting at $344
Looking for direct flights from São Paulo, Brazil to Santiago, Chile? Good news! There are direct flights available on this route, offering convenience and saving you time. Fly directly from São Paulo to Santiago with ease and explore the vibrant Chilean capital. If you prefer alternative routes or if direct flights are not available for your desired travel dates, worry not! There are several transfer options you can consider. Connect via other major South American cities like Buenos Aires, Lima, or Bogotá. These cities offer frequent connections to Santiago, making your journey smooth and hassle-free. At [air ticket search website], we make it easy to find the best flight options to suit your needs. By comparing prices and schedules from various airlines, you can choose the most convenient and affordable option for your São Paulo to Santiago trip. Start planning your South American adventure today!
Sao Paulo — Santiago
07/20/2026
Departure
Direct flight
JA773
starting at $116
Sao Paulo — Santiago
09/21/2026
Departure
Direct flight
JA773
starting at $118
Sao Paulo — Santiago
02/04/2026
Departure
Direct flight
H2611
starting at $125
Sao Paulo — Santiago
03/18/2026
Departure
Direct flight
LA751
starting at $130
Sao Paulo — Santiago
02/09/2026
Departure
Direct flight
H2611
starting at $133
Sao Paulo — Santiago
04/06/2026
Departure
Direct flight
LA753
starting at $135
Sao Paulo — Santiago
02/02/2026
Departure
Direct flight
H2611
starting at $135
Sao Paulo — Santiago
03/22/2026
Departure
Direct flight
H2611
starting at $135
Sao Paulo — Santiago
04/21/2026
Departure
Direct flight
LA757
starting at $135
Sao Paulo — Santiago
03/26/2026
Departure
Direct flight
LA633
starting at $137
LATAM Chile
Every day
starting at $130
Sky Airline
Every day
starting at $120
The cheapest one-way flight from Sao Paulo to Santiago departs on 07/20/2026, is operated by B&H Airlines and costs $116
The cheapest roundtrip flight from Sao Paulo to Santiago departs on 07/20/2026, is operated by B&H Airlines and costs $226
Fastest flight from Sao Paulo to Santiago takes 4h 5m
There are direct flights on this route 5 days a week: Su, Mo, Tu, We, and Th
The distance between Sao Paulo and Santiago is 2566km (1591 miles). The average flight duration is 4h 13m. There are 86 direct flights from Sao Paulo to Santiago. The time difference between Sao Paulo and Santiago is 1h. Flights from Sao Paulo begin at 5:45 AM. The latest flight from Sao Paulo departs at 1:50 AM
We couldn't find any special offers for flights from Sao Paulo to Santiago
The cheapest flight ticket from Sao Paulo to Santiago according to data for the last 48 hours costs $116
Often the best time to buy tickets from Sao Paulo to Santiago is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Sao Paulo to Santiago can be found flying in these months: July, September, December.
The fastest flights from Sao Paulo to Santiago start from 4 hours 5 minutes in the air.
The following airlines operate direct flights on the route Sao Paulo — Santiago: B&H Airlines, Sky Airline, LATAM Chile
The minimum one-way ticket price from Sao Paulo to Santiago is $116 (July 2026), while the maximum is $253 (March 2026). On average, a ticket costs $146–$160.