Turkish Airlines
Every day
starting at $1,246
Compare airlines, prices, and flight durations for your trip
Flaut.Travel was designed and developed by a team dedicated to making the process of searching, comparing and booking airline tickets as easy and convenient as possible. Our service helps travelers to find and buy the cheapest flights from Istanbul to Panama City. We have connected more than 40 airlines and airline ticketing agencies to help you find the most suitable and affordable flight option.
A non-stop flight is the most convenient and comfortable way to fly from Istanbul to Panama City, despite the fact that sometimes flights with transfers can cost significantly less.
A direct flight is the easiest way to get to your destination. The following airlines operate non-stop flights from Istanbul to Panama City:
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Answers to questions about the route that travelers are most interested in.
We keep tight track on airlines' pre-holidays sales and other special offers occurences all the time to let you save maximum amount of funds while traveling to your family or just going out on vacation.
Turkish Airlines
Every day
starting at $1,246
Istanbul — Panama City
02/03/2026
Departure
Direct flight
TK900
starting at $1,262
Istanbul — Panama City
02/04/2026
Departure
Direct flight
TK800
starting at $1,260
Istanbul — Panama City
02/05/2026
Departure
Direct flight
TK801
starting at $2,663
Istanbul — Panama City
02/06/2026
Departure
Direct flight
TK800
starting at $1,349
Istanbul — Panama City
02/07/2026
Departure
Direct flight
TK903
starting at $1,270
Istanbul — Panama City
02/08/2026
Departure
Direct flight
TK800
starting at $2,731
Istanbul — Panama City
02/09/2026
Departure
Direct flight
TK801
starting at $1,321
Istanbul — Panama City
02/11/2026
Departure
Direct flight
TK903
starting at $1,270
Istanbul — Panama City
02/12/2026
Departure
Direct flight
TK801
starting at $1,317
Istanbul — Panama City
02/13/2026
Departure
Direct flight
TK800
starting at $1,289
starting at $496
starting at $435
starting at $485
starting at $512
starting at $513
starting at $513
starting at $518
starting at $520
starting at $523
starting at $540
starting at $564
starting at $651
More than 12 airlines operate flights from Istanbul to Panama City, including Turkish Airlines, Valuair, Pegasus Airlines, Iberia, Sky Express, Wizz Air, Transavia, Animawings, Lufthansa, Scandinavian Airlines, LOT Polish Airlines, and Air Europa. This is a popular route, so passengers can choose tickets based on budget and preferences. Ticket prices start from $435, and our service lets you instantly compare all options. The variety of offers simplifies planning: you can choose budget fares or more comfortable options with baggage included or extra services. We help you find the best deals so your trip is cost-efficient.
The cheapest one-way flight from Istanbul to Panama City departs on 04/15/2026, is operated by Valuair and costs $435
The cheapest roundtrip flight from Istanbul to Panama City departs on 09/13/2026, is operated by Air Europa and costs $910
Fastest flight from Istanbul to Panama City takes 16 hours
There are direct flights on this route 7 days a week: Su, Mo, Tu, We, Th, Fr, and Sa
The distance between Istanbul and Panama City is 10850km (6727 miles). The average flight duration is 12h. There are 12 direct flights from Istanbul to Panama City. The time difference between Istanbul and Panama City is 8h. Flights from Istanbul begin at 8:00 AM. The latest flight from Istanbul departs at 1:50 PM
The cheapest flight ticket from Istanbul to Panama City according to data for the last 48 hours costs $435
Often the best time to buy tickets from Istanbul to Panama City is 2 months before departure.
Based on statistics over the past years, the lowest prices for flights from Istanbul to Panama City can be found flying in these months: June, February, April.
The fastest flights from Istanbul to Panama City start from 16 hours in the air.
The following airlines operate direct flights on the route Istanbul — Panama City: Turkish Airlines
The cost of a one-way flight from Istanbul to Panama City ranges from $479 (June 2026) to $1,091 (January 2027). On average, the ticket price is about $644–$647.
