Cheap Flights from Santiago to Istanbul — $508

The only airline operating direct flights from Santiago to Istanbul is Turkish Airlines. Flights operate every day except Wednesday and Thursday.

Santiago, Chile boasts two major airports, providing the perfect gateway for travelers departing the city. Arturo Merino Benitez International Airport, located 15 kilometers northwest of Santiago, serves as the primary hub and offers excellent connectivity to various destinations worldwide. Renowned airlines like LATAM, Sky Airline, and JetSMART operate here, ensuring a wide range of flight options. Arturo Merino Benitez Airport offers the convenience of multiple transportation alternatives, such as taxis, buses, and rental cars, ensuring easy access to the city center. Travelers will appreciate the minimal travel time and reasonable fares associated with these options. On the other hand, for those seeking a more expedient departure, Tobalaba Airport presents an advantageous alternative. Positioned just 30 minutes away from Santiago's downtown, this smaller airport is mainly used for domestic flights. Although it accommodates fewer airlines, the prestige of local carriers like Aerovías DAP and DHL Aviation ensures quality service and reliability. Tobalaba Airport's proximity to the city center enables travelers to save valuable time when reaching their departure point. With various transportation modes available, including taxis and ride-sharing services, the journey to Tobalaba is both swift and cost-effective. Whether you choose Arturo Merino Benitez Airport for international flights or Tobalaba Airport for domestic travel, both airports offer distinct advantages. Consider your preferences for flight options, travel time, and convenience when selecting the ideal departure point from Santiago.

The route Santiago — Istanbul is served by many carriers — 10 in total, including Turkish Airlines, LATAM Chile, Iberia, B&H Airlines, United Airlines, Sky Airline, Wamos Air, Avianca, Miami Air International, and Asian Air. This gives passengers wide opportunities: from finding the lowest fare (from $508) to selecting flights by schedule or service class. Our service aggregates data from multiple booking systems so you can compare offers in one place. This saves time and money: no need to check dozens of sites — just pick the right option and book online.

In different months, ticket prices from Santiago to Istanbul vary: minimum — $508 (December 2026), maximum — $1,105 (May 2027). Typically, the flight costs $763–$1,487.